Meet
Nicole Letourneau

Associate Principal

Nicole Letourneau, MPH, advises clients on policy and market-based strategies related to Medicaid drug policy and pricing, state policy, cell and gene therapy (CGT) development, value-based contracting, and innovative approaches to patient access.

In recent projects, Nicole has supported manufacturers assess how drug pricing reforms, including the interaction of the Inflation Reduction Act, and recent regulatory final rules will impact pipeline products. She has also helped CGT manufacturers identify and understand target patient populations, design and validate value- and outcomes-based contracting arrangements, anticipate reimbursement scenarios across channels and care settings, and develop stakeholder engagement strategies. Nicole also supports broader state engagement strategies to help life science manufacturers identify and develop state specific engagement strategies for Medicaid and commercial populations with respect to patient access.

Before joining Avalere, Nicole served as a public policy intern at ML Strategies, where she assessed the impact of public policy developments to support the client's advocacy priorities. Nicole also represented clients at congressional hearing and key stakeholder meetings. She holds a Master of Public Health in health policy from the George Washington University Milken Institute of Public Health and an BA in Human Development and Family Sciences and Public Health from Oregon State University.

Authored Content


State discretion over work requirement implementation may create significant variability, impacting patients, providers, and health plans.

Stakeholders can prepare for the upcoming implementation of federal Medicaid community engagement requirements, which are planned to go into effect January 1, 2027.

Changes in state and federal policies will drive patient access, financing, and provider reimbursement of cell and gene therapies.

Facing financial pressures, independent pharmacies adapt to remain viable, offering home delivery, vaccinations, compounding, and medication synchronization.

Limited access to AOMs across markets and a growing AOM pipeline will necessitate collaboration across manufacturers, payers, and the state/federal government.

Avalere Health finds that research funded by the Special Diabetes Program has yielded more than $50 billion in federal healthcare savings

Federal policymakers are considering Medicaid work requirements as a mechanism to reduce spending; recent state experiences offer important considerations.

If the ACA marketplace enhanced premium tax credits are made permanent, nearly 5 million people ages 50–64 will be eligible to receive premium subsidies in 2026.

Join us for a webinar exploring the RNA-Based Therapy landscape.

State Medicaid programs take a range of approaches to gene therapy coverage, management, and reimbursement.

If Mississippi expands Medicaid to 138% federal poverty level, Avalere estimates 125,000 uninsured individuals, ages 19-64, could gain coverage in 2025.

A white paper explores the RNA-based therapy pipeline and how FDA classifications can influence product development, commercialization, and patient access.

In this installment of our 2024 Trends Influencing Rare Disease series, Avalere experts explore policies shaping rare disease drug development and access.

The CGT Access Model will allow CMS to negotiate outcomes-based agreements on behalf of state Medicaid programs for CGTs, beginning with sickle cell disease.

The MDRP proposed rule's Best Price "stacking' provision has direct and indirect impacts on Medicaid rebate liability across drug classes.

The Hospital Insurance Trust Fund would remain solvent until 2048 if FFS utilization levels were similar to Medicare Advantage utilization levels.

Insurance coverage of anti-obesity medications is increasing, but patient access under Medicare remains uncertain.

Requiring manufacturers to stack all discounts provided through the supply chain could increase Medicaid rebate liability and complicate rebate dynamics.

Changes to rare disease policies and payers’ approaches to coverage could have significant impacts on product development, patient access, and reimbursement.

Starting July 1, manufacturers can report multiple best prices for some value-based arrangements, which may encourage broader use of innovative contracting.

The intersection of upcoming changes to drug pricing metrics will require new methods of calculating and reporting government pricing with implications for net pricing and contracting strategies.

Medicaid will continue to experience considerable changes at the state and federal levels, both in terms of beneficiary demographics and the payer landscape. Stakeholders should consider how upcoming elections, policy proposals, and COVID-19 will impact benefits and payer dynamics.

As control of the Medicaid drug benefit continues to shift from managed care organizations to states, manufacturers should understand unique benefit dynamics in each state, particularly as Medicaid enrollment is likely to increase amid the COVID-19 pandemic.